Medical+Science

__**Medical science: **__ Medicine has been an area in science where PCR is used ofetn.Cancer arises from the accumulation of inherited polymorphism (SNPs) and mutation and/or sporadic somatic polymorphism (i.e. non-germline polymorphism) in cell cycle, DNA repair, and growth signaling genes (Kirk et al.,2002). A reliable method to monitor progress of cancer therapeutic agents can be of immense use. RT PCR, currently the most sensitive method to quantify the specific DNA makes it possible to detect even a single molecule and diagnostics become feasible with lower amounts of complex biological materials compared to traditional methods ( Liefers, 2002 & Stahlberg 2005). In 2008 the detection of melanoma cells in the peripheral blood became a promising method for monitoring haematogenous spread of melanoma cells, however inconsistent data on the sensitivity and clinical relevance of this method have been reprted. As a result researchers developed a multimarker real-time reverse transcription- PCR (RT-PCR) for quantification of five melanoma markers: Melan-A, gp100, MAGE-3, MIA and tyrosinase (Arenberger et al, 2008). These markers will help detect cancer in its early stages and treatment can be carried out accordingly. PCR cancer researchhas helped doctors discover some of the molecular basis of cancer.

__**How Cancer Works:**__
media type="youtube" key="unTshYSctAQ?fs=1" height="385" width="480" Kent Onesemo (u3049020)